WASHINGTON – Artificial trans fats are officially banned. Once used in foods from popcorn to frozen pizza, artificial trans fats have disappeared from grocery stores and restaurants after the U.S. Food and Drug Administration (FDA) said they were not safe for human consumption in 2015, the Washington Post reports.

Consumption of trans fats have been declining for years, as food companies and restaurants removed them voluntarily from their products after researchers discovered the link between trans fats and heart disease. On Monday, the FDA’s artificial trans fats ban went into effect.

The ban was a long time coming, as the agency used gradual steps to help food makers adjust their products. In January 2006, the FDA mandated that artificial trans fats be included on food labels. By 2015, the agency decided trans fats weren’t safe for consumption, and put a ban in place for June 18, 2018.

The Grocery Manufacturers Association found that food manufacturers slashed trans fats 86% between 2006 and 2015, with 98% of trans fats disappearing from the U.S. food supply between 2015 and 2018, according to Brian Kennedy, an association spokesman. The agency is giving companies time to sell-through current stock. Some companies requested use of trans fats in certain circumstances, such as greasing baking pans, and the FDA agreed to a year’s extension for those requests.